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Applications of engineered exosome-based targeted strategies mainly include precision interventions involving: (1) Exosome-secreted protein biomarkers for PC. (2) Aberrantly expressed oncogenic exosome-secreted miRNAs. In this figure, we summarize some potential targets worthy of attention in future targeted strategies of PC

Journal: Journal of Nanobiotechnology

Article Title: Engineered exosomes: a promising approach for overcoming challenges in pancreatic cancer therapy

doi: 10.1186/s12951-025-03697-0

Figure Lengend Snippet: Applications of engineered exosome-based targeted strategies mainly include precision interventions involving: (1) Exosome-secreted protein biomarkers for PC. (2) Aberrantly expressed oncogenic exosome-secreted miRNAs. In this figure, we summarize some potential targets worthy of attention in future targeted strategies of PC

Article Snippet: In this figure, we summarize the sources of exosomes, valid cargos, engineering methods and therapeutic effects of some representative gene therapy experiments Fig. 6 Applications of engineered exosome-based targeted strategies mainly include precision interventions involving: (1) Exosome-secreted protein biomarkers for PC. (2) Aberrantly expressed oncogenic exosome-secreted miRNAs.

Techniques: